Upon the arrival of his long lost wife, Frankenstein agrees to join her in the ranks of S.H.A.D.E. (the Super Human Advanced Defense Executive), a highly secretive black ops super-agents team making their way to Europe to aid The Resistance. But first, the Creature Commandos will have to stop in Romania to find Nina’s father, the only person who might be able to save Griffith’s life after he is shot by a silver bullet.
As Frankenstein and his creature commandoes embark on their journey to find the cure for their afflictions, they’ll find themselves seeking Nina’s father’s old lab in Gotham. Unfortunately for them, however, a tracking device placed in their system in 1945 leads monster hunter Miranda Shrieve directly to their whereabouts.