A hyper-intelligent telepathic ape, Gorilla Grodd has sought to rule both the simian and human worlds, though the Flash has frequently thwarted his plans.
One of the most intelligent beings in the universe, the wicked Brainiac's genius has challenged Superman time and again.
Superman’s nemesis Lex Luthor may be the smartest criminal mind on Earth, but his intellect is no match for the alien artificial intelligence known as Brainiac. Nevertheless, Brainiac shares Luthor’s intense hatred of the Man of Steel, and has continued to use his Twelfth-Level intellect over the years to bring down the Last Son of Krypton.
Though he may appear to be little more than a greasy businessman, the manipulative Maxwell Lord has been the ringmaster of the Justice League, the world’s greatest spymaster, and an apocalyptic threat to metahumankind.
Like many of the most successful and influential people in the DC Universe, Maxwell Lord IV was born into money. His father was the CEO of a highly profitable but morally suspect pharmaceutical company, and when he killed himself upon discovering that they were releasing carcinogenic products, his surviving son resolved to put the family coffers to better use.